Details
Myocardial Troponin I (cTnI) is a protein of 22.5 kDa molecular weight found in the myocardium. Troponin I is a subunit of the three-part complex Troponin I, Troponin T and Troponin C. Together with tropomyosin, this structural complex is the major regulator of actomyosin calcium-sensitive ATPase activity in cardiac and striated muscle. Troponin I is released and released into the blood 4-6 hours after the onset of pain due to myocardial injury. The release process of Troponin I and CK-MB are similar, but while CK-MB levels decrease to normal within 72 hours, Troponin I levels remain elevated for 6-10 days, giving a longer time period for the detection of myocardial injury. cTnI specifically detects myocardial injury, as has been demonstrated in perioperative injury, marathon running and chest trauma. Myocardial Troponin I Rapid Test Card (Whole Blood/Serum/Plasma) uses a complex reaction of anti-cTnI antibody-coated particles and reagents for the qualitative detection of Troponin I in whole blood, serum or plasma. The minimum detectable Troponin I concentration is 0.5ng/ml.
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