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Menopause is the permanent cessation of menstruation, which is not usually diagnosed until after the menstrual cycle has stopped. The 12 months leading up to menopause are called premenopause. Many women experience symptoms of this period, such as hot flushes, irregular menstrual cycles, sleep disturbances, vaginal dryness, baldness, anxiety, mood swings, short-term memory loss and fatigue. The symptoms of premenopause are caused by changes in the levels of hormones produced by the female body that regulate the menstrual cycle. As the body produces less and less of the hormone oestrogen, it increases the production of follicle stimulating hormone (FSH), which would normally regulate ovulation. It follows that FSH testing can help to determine the age of premenopause. Detecting that premenopausal age has been reached allows appropriate steps to be taken to protect health and reduce the side-effects of menopause, such as osteoporosis, high blood pressure, high cholesterol and increased risk of heart disease.
The FSH Rapid Menopause Test Strip is a qualitative rapid test that detects FSH in urine with a sensitivity of 25 mIU/ml. The test uses a combination of monoclonal anti-FSH antibody to selectively detect elevated FSH levels.
The FSH Rapid Menopause Test Strip is a qualitative, planar flow immunochromatographic test for the detection of human follicle stimulating hormone (FSH) in urine to indicate the onset of female menopause. The test is based on a combination of antibodies and selectively detects elevated FSH levels using monoclonal anti-FSH antibodies. The test is performed by dipping a test strip into a urine sample and observing the formation of coloured band(s). The sample passes through the membrane by capillary action and reacts with the coloured conjugate. Positive samples react with the specific antibody to FSH on the membrane and form a coloured conjugate in the membrane test zone, which may be darker than the line in the reference control zone. The absence of this coloured line indicates a negative result. To verify the test, a coloured line always appears in the control zone, indicating that the sample volume is sufficient and membrane uptake was adequate.
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